Scientific And Medical References Proving Ozone's Validity As A Medical Treatment

By Ed McCabe  - www.misteroxygen.com

This is the most complete set of English language Ozone Medical  references available to date.  It took 7 years of hard  work against formidable opposition to bring this into existence  as a public service.  Therefore, Ed McCabe requests that his name always be associated with this publication.  It is copyrighted under: Ed  McCabe 1994. 

Chronological Ozone Medical References - Abbreviated List - With A Concentration On Successful Aids Research

Compiled from "O3 vs. AIDS" By Ed McCabe
Copyright (C.) 1991, 1992, 1993, 1994 by Ed McCabe

1896 Sept 22  Inventor genius Nikola Tesla patents the first  ozone generator in the U.S.

1898 Institute for Oxygen Therapy-Healing started in Berlin by  Thauerkauf and Luth.  First injection of ozone into animals, first  bonding of ozone to solid form products (Haemozon, now Homozon).   Proprietary bonding technology method still unknown and  unbelieved by all but certain American, German and Russian  scientists.  The chemistry is substantiated in Russian texts.

1898 Dr. Benedict Lust from Germany practicing in NY.  He was  the originator and founder of Naturopathy, and wrote many books  and articles on ozone.

1900 Medical ozone was used in the U.S. by Nikola Tesla who  formed the "Tesla Ozone Company" which was the first company to  use high voltage, high frequency, low amperage AC systems and  was granted many ozone patents.  Medical ozone and ozone  products were used widely in the beginning of the century and  their use actually predates the FDA's inception in 1906. 

1902 J.H. Clarke's "A dictionary of Practical Materia Medica,"   London, describes the successful medical use of "Oxygenium" in  treating Anemia, Cough, Cancer, Diabetes, Influenza, Morphine  poisoning, Canker Sores, Strychnine poisoning, Whooping-cough.  Oxygenium is ozone charged water.

1902 Dr. Chas. O. Linder M.D. was written up in Spokane, WA  "Centennial" magazine as injecting medical ozone and commonly  using state of the art ozone equipment in his medical practice.

1904 Ozone charged olive oil has been sold in pharmacies for  years all over the U.S. and used by thousands of physicians  under the trade name "Glycozone."  As reported in nineteenth  edition of "The Medical Uses of Hydrozone and Glycozone" by  Chas. Marchand. The New York Chemist's 339 page book is in the  Library of Congress with the U.S. Surgeon general's stamp of  approval on it.

1910 (+/-) Tesla's "Violet Ray" ozone producing device commonly  sold all over U.S. under many brand names and configurations,  even finding its way into the Sears catalogue.  Many had  provisions for therapeutic breathing of strong concentrations of  ozone after bubbling it through certain organic essential oils.   Violet Ray now available through all beauty supply shops in the  U.S..

Copyright 1911, 13, 15, 16, 19, 20 Noble M. Eberhart M.D., Ph.  D., D.C.L. was published by New Medicine Publishing Company. "A  Working Manual Of High Frequency Currents" Chapter 9 Ozone;  Nature; Physiological Action; Methods of Administration;  Diseases In Which It Is Indicated.  Dr. Eberhart was head of the  Department of Physiologic Therapeutics, Medical Department Of  Loyola University. Professor of High Frequency, Illinois School  of Electrotherapeutics. Head of Department of Electrotherapy,  Chicago College of Medicine and Surgery. Member of Chicago and  Illinois State Medical Societies, American Medical Association,  American Medical Editor's Association, Victoria Institute or  Philosophical Society of Great Britain.

He used ozone in Tuberculosis, Anemia and Chlorosis, Chronic  middle ear deafness and Tinnitus, Whooping Cough, Asthma,  Bronchitis and Hay Fever, Insomnia, Pneumonia, Nervous  Disability, Diabetes, Gout, and "Its beneficial action in  syphilis has been attested by many physicians."

"Ozonizing the air of a patients room is the best method of  employing ozone in this disease (tuberculosis)."

"In one sense of the word, since oxygen is so essential, it  might be easily claimed that ozone was indicated in any bodily  ailment... there are some diseases in which it is of particular  benefit.  Among these are anemia; all diseases off the  respiratory organs, including tuberculosis; infectious diseases;  and all conditions where there is imperfect oxidation and  impaired nutrition."

"H. de LaCoux, Chemical Expert to the Council of the Prefecture  of the Siene, Paris, says: "In the application of ozone for  tuberculosis, it is an undeniable clinical fact the number of  bacilli in the sputum diminishes after the second or third  treatment, even before the general condition of the patient is  improved."

"Dr. George Stoker, London, reports nine cases of tuberculosis  treated within a year at the Stoker Oxygen Hospital, of which  eight were discharged with the disease definitely arrested."

1913 Eastern American Association for Oxygen Therapy formed by  Dr. Blass and German associates

1914 Nov 20th, Dr. Charles O. Linder was advertising the  availability "At a great expense" on his part, of his new  medical ozone machine in the Vol 1 No. 1 "Not yet named  Magazine" at the Apple Show near Spokane, WA. He was passing the  ozone through Eucalyptus, Pine, and Cedar oils as scrubbers  before inhalation of the gas.

1920 Dr. Charles S. Neiswanger, M.D. publishes "Electro  Therapeutical Practice" Ritchie and Company, Chicago. "A Ready  Reference Guide for Physicians in the Use of Electricity and the  X-Rays." Chapter 32 "Ozone as a Therapeutic Agent."  Dr.  Neiswanger was the President and Professor General Electro- Therapy Illinois School of Electro Therapeutics; Chicago  Hospital College of Medicine. "Ozone acts as a powerful  antiseptic in contact with diseased mucous surfaces,  consequently its beneficial action is quickly apparent in the  treatment of bronchial and laryngeal affections, catarrh, hay  fever and all diseases of the respiratory organs."

1929  "Ozone and Its Therapeutic Action." Book names 114  diseases and applications of ozone and prints the research from  the centers and doctors centers using ozone. Armor Research  Foundation Institute of Technology, IL, American College of  Physical Therapy, Berlin University, Behren Memorial Hospital,  Glendale, CA, Board of Education, St. Louis, Bouvicant First  Hospital Paris, British Army Medical Service, London, Chicago  College Of Medicine and Surgery, Chicago, Harvard University,  Cambridge, MA, Polytechnic Institute, Brooklyn, NY, Physical  Chemistry University, IL, Post Graduate Medical School, NY, S.  California University of Los Angeles, Salaberry Hospital, Buenos  Aires, Spaulding General Hospital, Portland , OR, Western  Reserve University, Cleveland, OH, Washington University,  Seattle, WA.  A 40 page book with a different medical paper from  a different expert on each page.

1930 May 3rd, Journal of The American Medical Association  article: "The Therapeutic Use of Oxygen in Coronary Thrombosis"  by Robert L. Levy, M.D., and Alvan L. Barach, M.D. Oxygen tents  help oxygen starved heart attack victims.

1930 German dental physician E.A. Fisch was regularly using  ozone in his dental practice in Zurich Switzerland and writes  large number of ozone papers in Italian, French, and German.   Patents the "Cytozon," the first dental use ozone apparatus.

1931 Dr. Otto Warburg wins first Nobel Prize for work proving  cancer is caused by a lack of oxygen in the cells.  He states in  "The Prime Cause and Prevention of Cancer" that the cause of  cancer is no longer a mystery, we know it occurs whenever any  cell is denied 60% of its oxygen requirements.  This occurs  through a buildup of pollution or toxicity within and around the  cell which blocks and then damages the cellular oxygen  respiration mechanism.

1932 renowned Austrian surgeon Dr. Erwin Payr receives ozone  therapy and thereby learns of medical ozone by treatment from E.  A. Fisch.  Goes on to use ozone in his medical practice,  increasing its acceptability in surgery.

1935 Nov. Societe Francais d'Electrotherapie et de Radiologie  publishes M. Sourdeau (Le Mans) paper on "Ozone in Therapy" Four  machines to produce ozone have been installed in the Electro- Radiology service in Beaujon-Clichy.

1938  Parisian Medical Bulletin - Bul Med Paris 52 or 42:745- 749, Paul Aubourg, Honorary Electro-Radiologist in the Hospitals  of Paris, publishes "Medical Ozone: Production, Dosage, and  Methods of Clinical Application Using rectal insufflation he  noted that of 465 patients, the colon capacity varied from 150  to 800ccs (no megacolons), so everyone was x-ray photographed to  ascertain the proper dosage without forcing the ilio-caecal  valve. Ozone injections into wounds last for 6 to 15 minutes,  verified by laboratory bacteriological results. Vaginal  insufflations were common. Breathable concentrations of ozone  were routinely applied to infected sinuses. Intermuscular  injections were abandoned as too painful and ineffective. In  8000 applications of ozone, there were no accidents or harmful  side effects.

1938 Paul Aubourg "Results of 119 cases of coliform infection  treated by ozone in Beaujon-Clichy." Presse Med 1938; 46:1987- 1900.

1940's  German Doctor Hans Wolfe wrote the book "Medical Ozone." 

1940's FDA starts seizing ozone machines, and this policy  continues to this day.

1940's "Polyzone," "Aetheozone," and other ozone machines were  marketed in the U.S.

1942 "Gordon Detoxification and Hydro Surgery - Theory and  Practice" book published covering medical uses of ozone as colon  cleanser.

1943 During the Second World war, Dr. Robert Mayer treated the  FBI prisoners of war in the Ellis Island, NY POW camp.  Dr.  Mayer subsequently learned of medical ozone from one of the  German prisoners and has since been applying ozone to patients  in the United States for over 45 years.  Dr. Mayer is a  pediatrician, and has safely and effectively given ozone therapy  to over 12 thousand people, most of them children.  He pioneered  the technique of ozone being injected directly into the spinal  fluid to end meningitis.  Dr. Mayer has authored many medical  papers including:

"Using Ozone As A Chemotherapeutic Agent For the Treatment Of  Diseases" Out of compassion, he recently came out of retirement  (he's in his seventies) and began treating hundreds of AIDS  patients with medical ozone.

1944 Dr. Otto Warburg wins second Nobel Prize for his work  linking cancer to damaged cell respiration due to a lack of  oxygen at the cellular level.

1951 June Dr. William Turska, Chairman of the Committee on  Scientific Research of the American Naturopathic Association  publishes in the Journal of the American Naturopathic  Association "Oxidation." Dr. Turska pioneered the breathing of  Aethozol (ozone passed through selected oils). He also pioneered  and maintained one of the best methods of putting ozone into the  body was to put up to 250 cc's directly into the portal  circulation via the rectal veins with no pain, discomfort, or  side effects.  With repeated application, this completely cleans  the liver.

1953 Dr. Hans Wolff, general practitioner in Frankfurt, Germany  starts his own ozone clinic after coming into contact with and  learning about ozone from Dr. Hanseler.

1954 "Oxygen: Master Of Cancer" book published by Frank Totney.

1956 Feb 24  Two time Nobel Prize winner Dr. Otto Warburg (who  won this prestigious award for discovering and proving that  cellular respiration, once damaged by a lack of oxygen, caused  cells to mutate uncontrollably and turn into cancer cells)  publishes in SCIENCE 24 February 1956, Volume 123, Number 3191  "On the Origin Of Cancer Cells."

1958 - 1973  Dr. Robert Mayer and Dr. Edmund J. Ryan were  granted 8 ozone patents. 1950, 55, 58 patent # 3,063,904 granted  Nov. 13, 1962: "Polymeric Oxygen (Ozone) In Blood and Sera  Treatment and the Product Thereof."

1961 Encyclopedia of Chemical Technology, Volume 16, Third  Edition. John Wiley and Sons. The symptoms of breathing high  concentrations of ozone are acute, there appear to be no chronic  affects among normally healthy people because the body has the  ability to repair such damages. "No free radical reactions which  directly involve ozone have been observed. During the 80 year  history of the large scale usage of ozone, there has never been  a human death attributed to it." 

1965 Senator Edward Long holds U.S. Senate hearings where Dr.  Herbert Ley, FDA Commissioner testifies that the FDA "protects"  the big drug companies and are subsequently rewarded, and using  the government's police powers they attack those who threaten  the big drug companies.

"People think what the FDA is protecting them. It isn't. What  the FDA is doing and what the public thinks it's doing are as  different as night and day.

"First it is providing a means whereby key individuals on its  payroll are able to obtain both power and wealth through  granting special favors to certain politically influential  groups that are subject to its regulation. This activity is  similar to the 'protection racket' of organized crime: for a  price, one can induce FDA administrators to provide 'protection'  from the FDA itself."

Secondly, as a result of this political favoritism, the FDA has  become a primary factor in that formula whereby cartel oriented  companies in the food and drug industry are able to use the  police powers of government to harass or destroy their free  market competitors.

"And thirdly, the FDA occasionally does some genuine public good  with whatever energies it has left over after serving the vested  political and commercial interest of its first two activities."  - Barry Lynes, "The Healing of Cancer" Marcus Books,  Queensville, Ontario, Canada.

1966 June 20 Meeting of Nobel Laureates: "The Prime Cause and  Prevention of Cancer With Two Prefaces On Prevention." Dr.  Warburg delivers revised lecture at the meeting of the Nobel  Laureates at Lindau, Lake Constance, Germany.  He is the  Director of the Max Planck Institute For Cell Physiology, Berlin  Dahlmer; English edition published by Dean Burk, National Cancer  Institute, Bethesda Maryland, USA 1967.

1969 U.S. Congress studies the FDA and states that 37 of the top  49 officials of the FDA who left the agency moved into high  corporate positions with the large companies they had regulated.

1971 Dr. Hans Wolf (President) and Prof. Dr. Siegfried Rilling  (Vice President) founded The German Medical Society for Ozone  Therapy.

1972 The International Association For Oxygen Therapy, Dr.  George Freibott, President, emerges. Association formed out of  International Oxidation Institute, which came from the Eastern  American Association for Oxygen Therapy

1975 U.S. G.A.O. Government General Accounting Office studied  the FDA and revealed that 150 FDA officials owned stock in the  companies they were supposed to regulate.

1976 The FDA publishes in the Federal Register 21 CFR 801.415  Dated 2/13/76, amended 7/24/85, and 9/27/89: "Ozone is a toxic  gas with no known medical uses."  Ed McCabe comments in "The  Family News:" "Printing this statement in a publication paid for  with our taxes is either a blatant attempt at suppression of  truth from the highest levels, or one of the poorest research  jobs ever done.  It obviously favors competitive therapies, and  ignores well over 50 years of safe and effective medical use on  hundreds of thousands of humans - backed up with thousands of  medical references and clinical studies in Switzerland, Italy,  France, Germany, Australia, New Zealand, Mexico, and the U.S."

1978 FDA reports 1.5 million people were hospitalized in the USA  due to side effects from medication.  On the other hand, medical  ozone has been legally used in clinics worldwide on a daily  basis since the forties.  In Germany, Ozone side effects are  typically minor irritations that are caused by incorrect  application and quickly disappear.  This side effect rate is  incredibly far, far, lower than  U.S. drug therapy side effect  rates wherein each year approximately 140,000 people die from  prescription drug usage.  That's two and a half times more  Americans than were killed in Vietnam.

1979 First case of AIDS treated by medical ozone therapy.  Dr.  George Freibott, ND from the International Association of Oxygen  Therapy saw his first AIDS case.  A Haitian living in Avon Park,  Florida came to him with Kaposi's Sarcoma mouth lesions and was  treated with medical ozone in rectal insufflations, ozone  colonics, and direct ozone IV injection off and on for 1 1\2  years, only once a week.  All external lesions were healed.

1979 Dr Hans Wolff publishes his book on ozone.

1980 Aug 22nd Sweet F, Kao M S, Lee S-CD (Dept of obstetrics and  Gynecology, Washington University School of Medicine, St Louis,  Mo) and W. Hagar (St Louis Air Pollution Control) publish in  "Science" Vol 209: 931-933, a U.S. peer reviewed scientific  journal, their study: "Ozone Selectively Inhibits Human Cancer  Cell Growth." They announce "Evidently the mechanisms for  defense against ozone damage are impaired in human cancer  cells." "All of the cancer cells (lung, breast, uterine and  endometrial) showed marked dose-dependent growth inhibition in  ozone at .3 and .5 ppm" while the normal cells were not  affected. "Evidently cancer cells are less able to compensate  for the oxidative burden of ozone than normal cells." They also  stated that ozone inhibits cancer 40 to 60%, and up to 90% in a  dose dependant manner, yet there is no response from mainstream  medicine.

1980 Jan The German Medical Society for Ozone Therapy  commissioned Marie Theresa Jacobs and Prof. Dr. Dr. Hergetbegan  from the University Kilnikum Giessen and the Institute for  Medical Statistics and Documentation of Giessen University to  begin an inquiry entitled "Adverse Effects and Typical  Complications In Ozone Therapy." 2,815 questionnaires were sent  out to all western German ozone therapists known by the Medical  Society for Ozone Therapy (AGO, Arztliche Gesellschaft fur  Ozontherapie).  884 went to physicians and 1931 to therapists.

1980 May   By now, The German Medical Society had collected  1,044 replies, or 37% of the total.  The replies that were  returned stated 384,775 patients were treated with ozone with a  minimum of 5,579,238 applications and the side effect rate  observed was only .000005 per application! The report also  stated "The majority of adverse effects were caused by ignorance  about ozone therapy (operator error)."  The University of  Innsbruck's Forensic Institute published Dr. Zacob's  dissertation quoting this in The Empirical Medical Acts of  Germany.

1982 German medical textbook published: "Medical Ozone" 2nd Ed.  by Dr. Ewald Fischer Medical Publications in Heidelberg.

1983 "Ozone As Therapy In Herpes Simplex and Herpes Zoster  Diseases;" Mattassi R. MD, D'Angelo F. MD, Franchina A. MD,  Bassi, P. MD. Santa Corona Hospital, Division of Vascular  Surgery and Neurology, Milano, Italy 58 cases of Herpes Simplex  showed complete recovery in two to five days following ozone  therapy. "Results, Herpes Zoster: in all patients healing of  skin lesions were observed after a minimum of 5 and a maximum of  12 ozone injections.  Herpes Simplex: all patients healed after  1-5 injections. (Daily endovenous injections of 20cc of an  oxygen-ozone mixture.

1983 June  The chairman of neurosurgery at Jefferson Medical  College in Philadelphia, Dr. Jewell Osterholm, announced that  stroke damage can be reversed with spinal injections of an  oxygen-rich mixture.  Experiments on lab cats showed the  procedure does reverse stroke damage.

1983   May 24-25 - PROCEEDINGS - SIXTH WORLD OZONE CONFERENCE   Washington, D.C. 412 page book: "Medical Applications of Ozone."  

International M.D.'s List 33 Major Diseases
Successfully Treated With Ozone

"OZONE Removes viruses and bacteria from blood, human and   stored...  Successfully used on AIDS, Herpes, Hepatitis, Mononucleosis,  Cirrhosis of the liver, Gangrene, Cardiovascular Disease,  Arteriosclerosis, High Cholesterol, Cancerous Tumors, Lymphomas,  Leukemia..Highly effective on Rheumatoid and other Arthritis,  Allergies of all types...Improves Multiple Sclerosis,  ameliorates Alzheimers Disease, Senility, and  Parkinson's...Effective on Proctitis, Colitis, Prostrate,  Candidiasis, Trichomoniasis, Cystitis... Externally, ozone is  effective in treating Acne, burns, leg ulcers, open sores and  wounds, Eczema, and fungus."

1985 International Ozone Association publishes Robert A. Mayer's  Experience of a pediatrician using ozone as a chemotherapeutic  agent for the treatment of diseases of children. Medical  Applications of Ozone, Julius Laraus editor

1985 Jan "The Biochemical Process Underlying Ozone Therapy"  published in Germany by Renate Viebahn of Dr. J. Hansler GmbH,  Germany submitted for publication April 1984 accepted for  publication January 1985. Professor Viebahn is in constant  contact with most all of Europe's ozone using clinics. Her paper  demonstrates ozone's ability to ... disinfect and  sterilize...employ bactericidal and virucidal mechanisms...is a  circulatory enhancer...penetrates viruses.

1985 Sept "The Basic Clinical Applications of Ozone Therapy"  Siegfried Rilling, MD President of German Medical Association  for Ozone Therapy publishes in German medical publication,  received for publication January 1985, accepted for publication  September 1985. Complete descriptions of almost all ozone  therapies and suggested protocols, based on his lifetime of  clinical practice.

1986 Dr. Alexander Preuss  in Stuttgart, FRG, "Positive  Treatment Results in AIDS Therapy; OzoNachrichten 5 (1986) Heft  1/2, published case histories of AIDS patients treated with  ozone who are now completely healthy and back at work. Details  printed in "Oxygen Therapies" by Ed McCabe, Energy Publications,  1988.

1986, Dec 30, Patent # 4,632,980 was granted and now held by  Medizone, Inc. NYC, NY. "OZONE DECONTAMINATION OF BLOOD and BLOOD PRODUCTS" Medizone states all stored blood can be decontaminated with ozone, and  all HIV can be eliminated.  Medizone applies for human test  approval.  Despite 50 years of medical ozone's use on humans by  over 7,000 physicians, and flawless animal studies, the FDA  won't allow human testing in the U.S.

1987 Dr. Horst Kief, Heidelberg, FRG, announces successful  treatment of 3 AIDS patients brought from Stage 8 back to Stage  1  at his German clinic using autohemotherapy ozone/1 gram  vitamin C therapies.  Dr. Kief states "You can kill the AIDS  virus with ozone therapy... No side effects."  15 ARC patients  exhibit "full remission."  Gained weight, T cells went from 300  back up to 1500 (normal), gone back to work.  "One patient was  so weak he couldn't turn on the radio.  After only 3 treatments,  he walks to the bathroom unaided." Typical treatment twice a  week (method now outdated), continues for 7 to 11 months.

1987 Dr. Hans Neiper, an ozone using doctor in Hanover, FRG,  worked with NASA, past president of a German Oncology in an  interview by videographer Jeff Harsh, talks about his colon  cancer work.  Although he can't divulge the name of his  patients, "President Reagan is a very nice man."  And, "You  wouldn't believe how many FDA officials or relatives or  acquaintances of FDA officials come to see me as patients in  Hanover.  You wouldn't believe this, or directors of the  American Medical Association, or American Cancer Association, or  the presidents of orthodox cancer institutes. That's the fact."  

"The Use Of Ozone In Medicine"

1987 Classic medical ozone textbook published by Karl F. Haug,  Heidelberg, by Professor Siegfried Rilling, M.D. and Renate  Viebahn, Ph.D, co-authors.

225 OZONE MEDICAL REFERENCES AND

OVER 48 DISEASES COMMONLY TREATED WITH OZONE

Including: "Abscess, Acne, AIDS, Allergies, Anal Fissure,  Antiviral effect, Cerebral sclerosis, Circulatory disturbances,  Cirrhosis of the liver, Menopause, Constipation, Cystitis,  Bedsores, Dermatology, Fistulae, Funguses, Furunculosis,  Gangrene, Gastroenterology, Gerontology, Hepatitis, Herpes, High  Cholesterol, Colitis, Neurology, Dental Medicine, Tumors,  Cancer, Orthopedics, Osteomyelitis, Parkinson's, Rheumatism,  Proctology, Gynecology, Radiology, Raynaud's disease, Scars,  Inflammation of the vertebrae, Stomatitis, Joint dystrophy,  Surgery, Phlebitis, Open sores, Urology, Vascular surgery, Wound  Healing."

1987 March 8-12  K.S. Zanker presents ozone has benefit in  cancer treatment paper at the 2nd International Conference on  Anticarcinogenesis and Radiation Protection Gaithersburg  Maryland "The selectively inhibitive effect of medical ozone  prepared from pure oxygen on tumorous human cell cultures has  been known for a long time, and has recently been confirmed once  more." - Washuttl, Viebahn, and Steiner reviewing this study.

1987 Cuban (FDA equivalent) National Inst. For Scientific  Research conducts ozone animal studies proving ozone is non- toxic, non-mutagenic, non-carcinogenic. (Ozone won't cause  toxicity, mutations or cancer)

1987 Strahlenther Onkol (German Cancer Journal) 1987;163:37-42  "Zur Wirkung von Ozone und ionisierender Strahlung am In-Vitro- Modell - eine Pilotstudie an vier gynakologischen Tumoren" Karlic H., Kuccra H., Metka M., et al "Recently, evidence was  provided that ozone has a selective effect on an ovarian  carcinoma, two solid adenocarcinomas of the ovary and one  endomentrial carcinoma."  - (Zanker/Kroczeck)

1987?  FDA contacts 15-20 MD's who have bought Hansler German  ozone machines from a U.S. importer (McGrath/Boeve) and demands  they all turn in the generating tubes.  Some comply, some ignore  them.

1987 H G Knoch, W Roschke, W Klug publish in The German Articles  of Colo Proctology (Aktuelle Koloproktologie)  1987; Band 4:  161-173 "The use of Ozone Therapy In Proctology" (Die  Sauerstaff-Ozontherapie in der Proktologie" After studying the  work of Leipzig Surgeon E. Payer since 1936, they stated "It is  known that the rectal application of oxygen/ozone has a  therapeutical effect on diseases of the rectum and colon.

Animals. Animal experiments were conducted to clarify the O2  diffusion through the wall of the colon, and the increase of PO2  in the venous and arterial blood flow...when O2 and O2/O3 gas  insufflation was applied." Using 10 rabbits averaging 2500 g  rectal insufflation was applied.  After O2/O3 gas was applied at  5.1 mg over 10 seconds, the PaO2 was up 300%. O2 diffuses  through the wall of the colon and increases the O2 concentration  in the vascular system and the liver.

"Due to the known properties of ozone (bactericidal, circulatory  enhancement, virucidal, fungicidal, hemostatic, wound leaning  and metabolic stimulant), its rectal application is also  recommended for human patients."

Clinical human examinations: "An adult human tolerates 800 ml of  an ozone/oxygen gas mixture applied rectally over a period of  one minute without any complaints." "Gas absorption is slow, on  average within one hour." Both the oxygen and the oxygen/ozone  mixture is absorbed through the wall of the large intestine,  enters the blood stream and results in a PaO2 increase within  the entire organism." "No adverse effects occur when ozone is  applied."

(Ozone is) Recommended for colitis and proctitis and is  "superior to all previously known methods of therapy. In  proctology, we view the indication of rectal insufflation to be  valid for colitis."  " 16 patients with hepatitis B were given  ozone and compared to a control group. Those who got the ozone  had an increase in wellbeing and 75% of those treated could be  placed in the "healed" category within a period of 14 days.

1988 Historian Eustice Mullins writes: "The Office of Technology  Assessment of the U.S. Government states that 95% of the  prescription and over the counter drugs on the market have not  been proven to work." 

1988  "International Bio-Oxidative Medical Foundation" Charles  H. Farr, M.D. President, is formed by several hundred U.S.  M.D.'s trying to advance oxygen therapies in the U.S. by  publishing their successful clinical results.  Yearly meetings  attended by physicians from all over the world.

1988    Dr. Gerard Sunnen publishes: "Ozone in Medicine:  Overview and Future Directions" in The Journal of Advancement in  Medicine. Dr. Sunnen, at the Bellevue Medical Center in New York  City, lists medical ozone as commonly being used worldwide on:  "Herpes, AIDS, and Flu.  Wounds, burns, staph infections, fungal  and radiation injuries, and gangrene.  Colitis, fistulae,  hemorrhoids and anal infections.  It promotes healing.  Blood  ozone treatments have been used to treat virus infections  including: AIDS, hepatitis, flu, some cancers, diabetes and  arteriosclerosis. Used in dental surgery, periodontal disease,  mixed in water and swallowed for use on gastric cancer, and  applied as a wash in intestinal or bladder inflammation.  Mixed  with olive oil it is used on fungal growths and skin ulcers.   Ozone baths are used to irrigate the skin, to disinfect and  treat eczema and skin ulcers.  "All of the world's blood  supplies may be made bacteria and virus free (AIDS, etc.) by  passing 40-50 mcg/ml of ozone through them."

1988 "OXYGEN THERAPIES" book by Ed McCabe lists 5 AIDS case  histories showing successful treatment by ozone, and lay  translation of paper based upon 74 medical references proving  ozone's effectiveness in disease treatment.  First widely  distributed international publication in history to describe  effectiveness of every known oxygen therapy, those being  commonly self administered, and those administered under a  physician's care. Becomes best seller.

1988 June Dr. Scott Ricke and inventor Basil Wainwright  conducted an HIV in vivo scientific study involving five  patients in Nogales, Mexico.  In just ten days of treatment,  Ozone and a new AIDS monoclonal measurement process developed by  Epitope, Inc. demonstrated a reduction of 28% and higher of  viral activity.

1988 July "The Treatment of Viral Diseases with Ozone" published  in "Erfahrungsheilkunde,"  Number 7, July 1988 by Dr. Horst Kief  "Ozone is highly effective against viruses... The present study  provides statistical proof of its extraordinary efficacy in  cases of chronic aggressive hepatitis... In the case of AIDS and  ARC patients,... hyperbaric ozone therapy can lead to  astonishing improvement in the clinical status..."

1988 Sept Dr. William Closon, M.D. working with Basil Wainwright  at Brunswick Blood Laboratories establish that the precise non- cytotoxic window of ozone concentration to achieve maximum HIV  viral inactivation is 2% by weight, or approximately 27  micrograms per milliliter.

1988? Boguslaw Lipinski, Ph.D., Boston Cardiovascular Health  Center and Tufts University School of Medicine, Wellesley, MA  publishes "Rationale For Treatment Of Cancer With Ozone." Citing 35 medical references, Dr. Lipinski concludes  "Preliminary clinical studies indicate that oxidative therapy  might produce desirable results in cancer treatment."

1988 Sep Dr. Horst Kief presents his findings at the Fourth  International Conference on AIDS. He followed 13 AIDS patients  for 12 months of treatment, Kief suggested that the absolute CD- 4 count could be increased in such patients and their T$/T*  quotient returned towards normal through ozone Therapy.

1989 William Campbell Douglass, M.D. publishes "AIDS, The End Of  Civilization" In it he says, "At present we have the ambulance- at-the-bottom-of-the-cliff mentality in which the only solution  entertained is to pick up the bodies rather than go to the top  of the cliff and solve the problem." Dr. Douglass visited scores  of empty villages in Africa where whole tribes had died of AIDS.   He reports seeing mound after mound of burial sites along  roadsides in which natives were buried when and where they fell  dead.  Dr. Douglass now actively promoting blood ozonation\UV  (photophoresis) treatments in the U.S.

1989 April-May  Raum and Zeit Vol 1, No. 1, "The Treatment of  Virus Infections with Ozone-Oxygen Mixtures;" Alexander Preuss  M.D. (Preuss's work was featured in Ed McCabe's book "Oxygen  Therapies" in 1988) He cites 8 of his AIDS case studies wherein  ozone therapy had dramatically improved their health.   "Therefore I may conclude that AIDS in the state of an  opportunistic infection is treatable for at least 17 months -  nobody has to die from it any longer."

1989 July "Ozone Science and Engineering" Vol 11 pp. 411-417   publishes Immunological Examinations In Patients With Chronic  Conditions Under Administration Of Ozone/Oxygen Mixtures;" J.  Washutti, R. Viebahn, I. Steiner  "... a significant increase in  IgG, the most important immunoglobulin in the immune system...  must be assessed as an immunostimulation.  ...no  immunosuppresive effect occurs,... On a long term basis, no kind  of immunosuppressive behavior caused by ozone application can be  found in the dosage range selected.

1989 July 6th  "Ozone Science and Engineering" Vol 12 pp 65-72  publishes The Influence Of ozone On Tumor Tissue In Comparison  With Healthy Tissue" J. Washuttl, R. Viebahn, I. Steiner "The in  vitro results clearly show that a pronounced influence on tumor  metabolism, which does not occur in healthy tissue, is indeed  possible with ozone. Because, here in particular, the  respiratory cycle and glycolysis as well as general oxygen  utilization in tumor tissue are positively influenced by ozone  therapy..."  

1989 Aug 8th  "Newsweek" Vol. 114, No.6, P. 50 A highly  developed AIDS underground composed of entrepreneurs and AIDS  activists smuggles unsanctioned drugs and even an ozone- injection machine into the United States. Desperate people feel  the underground network is the only hope they have.

1989 Sep Dr. Harald Vetter ND of 8126 Hohenpeissenberg, Germany  publishes "AIDS, Can Ozone Help?" the meticulously documented  results of his application of 600 ml autohemotherapy ozone  therapies to 100 patients with AIDS (44 with AIDS / WR 6, 47  with ARC / WR 3-5, 9 with Lymphadenopathy (LAS) / WR 1-2. An  insurance expert reviewed a typical case and declared such  dramatic improvements are in fact almost incredible.

1988 Oct 26 Associated Press "Ozone may limit AIDS Symptoms?"  Bethesda Naval Hospital's Dr. Kenneth Wagner reports ozone  stopped the HIV virus from multiplying, and left cells  undamaged. Dr. Steven Kleinman from The American Red Cross says  it should be experimented with further.  AP then reports on Dr.  Carpendale, Chief of Rehabilitative Services at the San  Francisco VA Hospital's ozone study controlling diarrhea, and  possibly hindering the AIDS virus.

1988 Nov 28  "Insight" Vol. 4, No. 48, P. 56 by Dina Van Pelt.  Ozone may be able to kill HIV without harming infected blood  cells. The Bethesda Naval Hospital in Maryland conducted tests  on HIV infected blood in which ozone killed the virus without  damaging the cells that contained it. Dr. Kenneth F. Wagner,  senior research physician for HIV research at the Henry M.  Jackson Foundation for the Advancement of Military Medicine in  Rockville, MD., says that European physicians have safely used  ozone to safely treat viruses for years. In a study of five  patients at San Francisco's VA Hospital, all five showed  significant improvement without signs of toxicity.

1989      FIRST MODERN U.S. HOSPITAL TEST OF OZONE ON HUMANS  STOPPED George Perez, M.D., Dir. of Virology at Saint Michaels Med  Center, Newark, NJ, and Chief Investigator of the hospital's  Institutional Review Board was commissioned to undertake a 75  day institutional review board supervised ozone/AIDS protocol.   5 terminally ill AIDS patients underwent only 15 days of ozone  treatments at Saint Michaels Hospital in Newark, New Jersey.   The T4 counts of the patients were from a low of 5 to a high of  86. At the start, one was so badly covered with herpes lesions  he couldn't wear clothes.  All had T-cell counts of below 200.   By the end of the 15 days each treatments, the herpes patient's  skin had healed, and all had been released from the hospital. No  adverse side effects or toxicity could be found.  T/4 counts  remained stable or increased. Viral protein core (p24) counts  decreased - indicating mass virus destruction.  Four M.D.'s  state ozone therapy is non toxic, and should be adopted. Due to  political pressure, the tests were aborted.

Comment:  "Political pressure" means that after the fact, the  FDA forced Dr. Perez to sign a bogus statement that ozone is  "worthless," or he was through as a doctor, and the hospital  would never get any more millions in funding.  Heavily censored  copies of this are available through the Freedom of Information  Act.

1989 Nov Cuban M.D.'s successfully treating sickle cell anemia,  ankle ulcers, farm accidents, and ocular (RP, retinitis  pigmentosa) disease. James Caplan, CAPMED/USA and Dr. Manuel  Gomez, National Institute for Scientific Research, Havana, Cuba  have patent pending for treating sickle cell anemia disease  crises and ulcers with oxygen/ozone.  They began large scale  human trials leading to Cuban Ministry of Health approval for  general use of ozone for sickle cell anemia, ulcers, and topical  wounds.  Ozone had been approved for the treatment of retinitis  pigmentosa before the sickle cell anemia started.

1989 "Ozone In Medicine, Vol 3" Proceedings of The Ninth World  Ozone Congress, New York, published by International Ozone  Association of Zurich. 14 presentations of the medical  therapeutic applications of medical ozone by bona fide  international M.D.'s and scientists.

1990 Jan 24  The Canadian National Defence Headquarters wrote to  Health and Welfare Canada Bureau of Biologics, "Ozone Therapy in  AIDS / project #231, Summary of Findings." Significant positive response in CD4 counts. No detrimental  effects on absolute CD4 counts. "Contrasted with the control samples which quickly became (highly) positive for HIV-1...These  data clearly demonstrate that no HIV-1 activity was detectable  in any of the ozone-treated samples.It would appear that this  form of therapy constitutes a potent means of inactivating HIV-1  in contaminated blood supplies, and may also provide a means for  patient specific  "autovaccination" in selected cases." They  strongly asked for more funding to continue the research.

1990 Experimental Chemotherapy 1990;36:147-154 "In vitro  Synergistic Activity of 5-Fluorouracil with Low-Dose Ozone  against a Chemoresistant Tumor Cell Line and Fresh Human Tumor  Cells" "Our results indicate that ozone in combination with 5- fluorouracil (5-FU) makes a 5-FU resistant cell line susceptible  for the combined treatment modality. Furthermore, ozone acts  synergistically or at least additive to chemotherapy in  different tumor cell suspensions, derived from the breast and  the colon."

1990  April-May  University of Bologna Italy department of  optical physiology publishes in Panminerva Medica"Effects of  Oxygen-Ozone Therapy on Age Related Retinal Macular  Degeneration" "The majority of patients showed an improvement of  their ocular condition."

1990 Haematologica, 1990 75:510-5, famous European Medical  Journal publishes the work of Velio Bocci and Luana Paulesu  "Studies On the Biological Effects of Ozone 1. Induction of  Interferon On Human Leucocytes." sponsored by grants from the  Italian Ministry of Education. "...ozonation of blood is a  medical procedure followed in several countries for treatment of  viral diseases... we feel that the exploration of the effects of  ozone on PBMC (peripheral blood mononuclear cells) has opened a  new field of investigation that may yield useful results both in  biological and practical terms. Ozone or its reactive oxygen  species may act mainly via the stimulation of PBMC and release  of lymphokines. The hypothesis can be made that ozone could lead  to the release of tumor necrosis factor (TNF), interleukins  (Ils) and IFN (interferon, a powerful antiviral protein with  immunomodulatory activities could produce some benefits in  patients with viral diseases)." (See the rest of the study 1991,  Nov 5th)

1991 Susan M. Lark, M.D. Los Altos, CA sends Ed McCabe a draft  copy of her article entitled "Ozone and Its Uses In Medical  Therapy".  She reviewed the reseach studies on ozone therapy and  concluded "the studies find bennefit in the clinical use of  ozone for a varitey of conditions with a minumum of side  effects."  She told Ed "After a decade of product  development/research with oxidative modalities, I have found  ozone/oxygen therapy to be one of the most powerful and  effective therapeutic modalities I have ever worked with."

1991 March,  Proceedings of the 10th World Ozone Conference in  Monaco " The efficacy of O2/O3 Low Pressure Application In Badly  Healing Wounds" Horst Werkmeister - Former head of the  Radiography Department, Lutheran Hospital, Oberhausen Germany.  "There is little inconvenience to the patient, ozone is not  capable of engendering further damage, and produces a  significant stimulation of wound healing in a large number of  cases due to its disinfectant and pronouncedly hyperemizing  effect.  If applied early enough, it is often able to prevent  the development of large lesions.  The unprejudiced presentation  of wound developments following the application of ozone/oxygen  gas treatment on the basis of measurement values given above has  the aim of encouraging a wider and more frequent application of  this method as it has shown its efficacy in many severely  affected patients."

1991 March,  Proceedings of the 10th World Ozone Conference in  Monaco "Resolution of Intractable Diarrhea of Unknown Etiology  in Patients With AIDS Treated by Medical Ozone - A pilot study."  Ozone rectal insufflation stops AIDS patients' diarrhea.

1991 Apr  Erfahrungsheilkunde Vol 40, No. 4 "Ozone Therapy - The  underlying Therapeutical Concept And Models Of Efficacy." Renate  Viebahn-Hansler "Due to its very specific reaction, medical  ozone, as a pharmaceutical agent, has an accurately defined  range of efficacy... According to the dosage and concentration  range, we make use of the different properties of ozone, i.e.:  its germicidal action (by oxidative destruction), its inability  to inactivate microorganisms, and its restitutional effect (at a  low concentration range).  This involves three major  indications: external ulcers and severe skin lesions, diseases  of viral and bacterial origin, and arterial circulatory  disturbances.  The restitutional effect of ozone can be  understood via its oxidative influence on the oxygen metabolism,  the induction of specific enzymes and the activation of  immunocompetent cells.

1991 Oct 1 Peer reviewed "JOURNAL OF THE AMERICAN SOCIETY OF  HEMATOLOGY" In a major breakthrough for U.S. medical thinking, three years  after the study concluded, the ozone\HIV work of M.D.'s  Wells,  Latino, Galvachin, and Poiesz is published in a well respected  U.S. peer reviewed medical journal. Their article:

"Inactivation Of HIV Type 1 by Ozone In Vitro" appears in "Blood Journal, Volume 78 Number 7, Oct 11, 1991, pg.  1882" describing the research coordinated by Dr. Bernard Poiesz  from Syracuse State University of New York Research Hospital.   They performed 15 replications of an ozone study that interfaced  ozone with HIV infected factor 8 blood.  The ozone completely  removed the HIV virus from the blood 97 to 100% of the time, yet  was non-toxic to normal healthy blood components.  Ed McCabe  announced this study back in 1988, in his "Oxygen Therapies"  book.

1991 OCT  Dr. Michael T. Carpendale M.D.  Veteran's  Administration Hospital, San Francisco, and Joel Freeberg M.D., UC  Medical School San Francisco, Bay Medical Research Foundation,  San Francisco, publish in The Journal of Antiviral Research  1991; Volume 16 Number 3 :281-292 the following medical paper:

"Ozone Inactivates HIV At Noncytotoxic Concentrations "HIV (p24) was reduced in all ozone treated cultures compared   to controls."

Dr. Carpendale also privately published "Ozone Treated HIV+  patient Becomes PCR Negative", the stories of two ozone rectal  insufflation using AIDS patients - one who became PCR-.

1991 Dr. Robert Mayer (using ozone over 50 years, since the  forties) has late stage AIDS patients in his research center  clinical study some who only have a count of 5 T cells.  Normal  is 600-1500+.  Although they have a count of only 5 T cells,  they are completely healthy. In a hope indicating development,  local FDA office told Dr. Mayer to go ahead and use ozone, as  long as he only makes it himself in his own office with his own  self manufactured machine.

1991 A brave humanitarian U.S. M.D. (Dr. J.B., ret.) in a  southern state comes forward with his secret clinical  ozone/hyperbaric therapy results.  All his testing was performed  at a major hospital and within independent labs.  Out of 248 HIV  POSITIVE patients he reported bringing 113 to HIV NEGATIVE, each  within 60 Days, using ozone autohemotherapy immediately followed  by hyperbaric therapy.

1991 Publication: The use of ozone-treated blood in the therapy  of HIV infection and immune disease - a pilot study of ozone  safety and efficacy.  "AIDS" 5:981-984.  G. Garber, D Cameron, N  Hawley-Foss, D Greenway and M. Shannon.

This is the study the detractors of ozone like to quote to  falsely try and prove it doesn't work.  In an early Canadian  establishment attempt to see if there is any validity to ozone,  and to see if it was safe, a poorly designed and executed  protocol was used in a pilot study by well meaning but  unexperienced practitioners. The trial was sponsored by the  Ottawa General Hospital Infectious Disease Division, Canadian  Health and Welfare, Canadian Federal Center For AIDS, Department  Of National Defence, and The Meuller Medical Company of Canada. 

Comment: Poorly designed because the study only gave 10cc's of  ozone into a muscle (dismissed by Aubourg in 1938 as too painful  and ineffective), not I.V., and not enough to do any good, and  not for a long enough time period. How are you going to clean up  the 100 plus pounds of water that humans are by putting 10cc's  into a muscle only three times a week? The daily environmental  toxic load intake on the body alone would quickly negate any  benefit, let alone the stress of a disease like AIDS!

Poorly executed because during the second half of the too short  study, the principals admitted the ozone machine had broken, and  wasn't producing any ozone, yet they ignored this fact when they  wrote up the second phase of the study! 

So, they used a protocol that any serious practitioner would  laugh at, and based their conclusions upon false data.  They  then compounded their errors by seriously overstepping their  boundaries and wrongly making the unjustified broad  pronouncement that "Ozone therapy does not enhance parameters of  immune activation nor does it diminish measurable p24 antigen in  HIV-infected individuals."

The tragedy of allowing such studies to be published, and such  pronouncements to be made, is that this false conclusion is  often repeated by the FDA to our elected representatives while  they ignore the thousands of studies that show ozone does work.   This intellectual dishonesty is used to politically justify  barring further real research that would eliminate suffering and  save lives.

1991 Nov 5th  Lymphokine and Cytokine Research Vol 10, Number 5,  1991 publishes "Studies on the Biological Effects of Ozone: 2.  Induction of Tumor Necrosis Factor on Human Leucocytes, Luana  Paulesu, Enrico Luzzi, and Velio Bocci. "Because ozonation of  blood is a procedure followed in several European countries for  the treatment of viral diseases and tumors, the release of  factors with antiviral and immunomodulatory activities by  leukocytes may explain the mechanism of action of ozone and of  autohemotherapy." The "ozone concentration is critical in terms  of TNF production and of cell mitogenesis. Owing to the presence  of erythrocytes, higher concentrations are required to be  effective in blood than in PBMC."

1991 Dec Dr. Robert Mayer joins the doctors reporting patients  sero-converted to HIV NEGATIVE through use of ozone  autohemotherapy.

1991 Major northeast area university scientist in conjunction  with BSME engineer/researcher J.W. (names withheld by request to  prevent being closed down by big money interests) undertaking  two year plus microbe group eradication study using ozone  equipment.  Reporting 100% kill in vitro in 20 studies  completed.  Ft. Lauderdale police sergeant associated with FL  Wainwright case phones one of the researchers and warns them, "You  will be part of a criminal conspiracy if you continue to study  ozone's effectiveness."

1991 Medizone ozone company negotiating with Canadian Armed  Forces to commence 2 1\2 million dollar ozone research study to  commence in 1992, comprised of animal studies, blood  sterilization studies, human trials, the works.

1992 Jan Captain Michael Shannon, Deputy Surgeon General for the  Canadian Naval Forces has 350 scientists under him.  He is  commencing a 2 1/2 million dollar ozone medical research study  that will including blood sterilization, animal trials, and  more. The Canadian Government realized that if a major event  occurs, their army's blood supply would be inadequate in its  present condition. He states "With thousands of people going to  Europe yearly at a considerable cost to get this treatment -  there must be something to it."

1992 May 8th Associated Press: Dr. Wayne Jonas, Walter Reed Army  Institute of Research. Testifies before the North Carolina  legislative panel.  "Requiring that current medical practices be  based on solid scientific evidence is building our house on a  rock.  Requiring that such practices be 'prevailing' is building  that house on sand.  What is prevailing in medical practice  shifts with the wind of opinion and the tide of profit."

1992 June Author Ed McCabe begins working closely with former  U.S. Congressman Berkeley Bedell.  They decide to have Ed  invited to testify before the newly-created National Institute  of Health's Office of Unconventional Medicine.  He testifies  that, "Due to the many interviews I have conducted, it is my  opinion that the AIDS problem has been solved.  If immunity from  state, and federal, and agency, and medical board prosecution  could be assured, these humanitarian doctors would gladly make  available their knowledge for the public good. I stand ready to  do the same.  They don't even need your money, they'll fund it  themselves.  If we can get ozone doctors immunity from  prosecution, within 90 days the only thing left to do would be  to implement the existing solution."

Ed and Berkeley decided that they need an MD to be there as  well, and chose Dr. John Pittman from North Carolina to  represent the ozone using doctors undergoing political  harassment.  Dr. Pittman told his story of being closed down  even though the therapy was working.

1992 June  Ed McCabe and Dr. John Pittman meet with Dr Killian,  Deputy Director of the NIH's N.I.A.I.D. (AIDS institute). He and  his assistant were very enthusiastic about ozone once they saw  the proof they were brought that ozone was successful in  treating AIDS patients.  Later, upon follow up, they were very  closed mouthed, without enthusiasm, and acted like they never  heard a word they were told.

1992  Bolton, A. "Report on Scientific Studies to Elucidate  "Ozon-O-Med" Treatment of Peripheral Vascular Disease" Intermune  Life Sciences, Etobicoke, Ontario, 1992

1992 July  Ed McCabe went to Washington  on July 22nd, 1992.   The trip was made after setting up private meetings with 2 U.S.  Congressmen to coincide with the meeting that former Iowa  Congressman Berkly Bedell and Ed McCabe had set up on the same  day with U.S. Senator Tom Harkin, the former Presidential  Candidate. 

Mr. Bedell and Mr. McCabe decided to invite 2 doctors that had  each brought a patient from HIV+ to HIV-.  They also invited Jim  Caplan, the man responsible for convincing the Cubans to approve  medical ozone therapy for general use, and Dr. John Pittman, an  ozone using doctor, and one of his recently denied treatment  AIDS patients.  Dr. Pittman's office was closed down by the  North Carolina state medical board in the middle of successful  clinical ozone trials due to "ozone not being FDA approved."   They visited the Congressmen, were warmly received at each  meeting, and ended up in turn at Senator Harkin's office for our  meeting with him, where they were joined at this point by Dr.  Michael Carpendale and his boss from the San Francisco Veterans  Administration Hospital.

Senator Harkin scheduled us for only a 1/2 hour meeting, but he  was so intrigued by our pr